Relationship between Hypothalamic-pituitary-adrenal axis and Executive Functions in Chronic Methamphetamine Users, a Cross-Sectional Study

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20180402001

Enrollment

Registered

2018-04-02

Start date

2015-03-15

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

All stages of the study were conducted after obtaining informed consent and based on the latest version of Helsinki Declaration. Hypothalamic&#45

Interventions

None listed

Eligibility

Sex/Gender

Male

Age

25 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria were including the age range of 25-65 years, the methamphetamine dependency based on DSM-IV, the history of addiction between 2 to 10 years, and the amount of use between 0.5 to 1 g / day, minimal ability of reading and writing, and staying in Tehran and its suburbs at a distance of 30 square kilometers.

Exclusion criteria

Exclusion criteria: Exclusion criteria were also including co-dependence on other drugs, drug use during the 12 months prior to preliminary assessment, history of kidney stones, renal failure, or Kidney transplantation, the history of specific diseases, severe psychiatric disorders, and the use of antipsychotics drugs and drug allergy.

Design outcomes

Primary

Measure	Time frame
Plasma serum cortisol levels 12 weeks radioimmunoassay (RIA)	—

Secondary

Measure	Time frame
executive functions 12 weeks Wisconsin Card Sorting Test (WCST)	—

Countries

iran

Contacts

Public Contactbijan pirnia

Bijan Center

b.pirnia@usc.ac.ir+9802122081450

Outcome results