FindTrial
Sign In

Effectiveness of Budesonide-Impregnated Absorbable Nasal Dressing Following Endoscopic Sinus Surgery

Effectiveness of Budesonide-Impregnated Absorbable Nasal Dressing Following Endoscopic Sinus Surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
TCTR
Registry ID
TCTR20180323002
Enrollment
Unknown
Registered
2018-03-23
Start date
2018-08-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic rhinosinusitis with nasal polyps Budesonide&#44

Interventions

Budesonide inhalation suspension 0.5 mg/2ml&#45
impregnated absorbable nasal dressing (polyurethane foam) following endoscopic sinus surgery,Normal saline&#45
soaked absorbable nasal dressing (poly urethane foam) following endoscopic sinus surgery
Experimental Drug,Placebo Comparator Drug
Budesonide inhalation suspension,Normal saline

Sponsors

Faculty of Medicine, Chulalongkorn University
Lead Sponsor
Department of Otolaryngology
Collaborator

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.Diagnosis of chronic rhinosinusitis with nasal polyps according to EPOS 2012 guidelines 2.Refractory chronic rhinosinusitis with nasal polyps 3.Minimum preoperative Lund-McKay computed tomography score of 6 per side 4.Planned surgical intervention required bilateral ESS of all sinuses

Exclusion criteria

Exclusion criteria: 1.Oral steroid-dependent condition 2.History of intolerance to corticosteroid 3.Immunodeficiency 4.Diabetes mellitus 5.History of glaucoma 6.Allergic fungal rhinosinusitis (endoscopic findings of allergic mucin and classic CT scan findings) 7.Mucociliary disorders 8.Pregnant 9.Unable to give written informed consent

Design outcomes

Primary

MeasureTime frame
Endoscopic score 2 and 4 week POSE scoring system—

Secondary

MeasureTime frame
Infection rates 2 and 4 week yes or no,Satisfaction to debridement 2 and 4 week Visual analog scale—

Countries

Thailand

Contacts

Public ContactOnusa Taweewuthisub

Department of Otolaryngology, Faculty of Medicine, Chulalongkorn University

onusa0211@gmail.com089-120-0211

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026