Patients visit emergency room at King chulalongkorn memorial hospital (KCMH) Age between 18-
Conditions
Interventions
Control group : Chorpheniramine 10 mg/amp
1 ampule and cetirizine 10 mg 7 tabs,Chorpheniramine 10 mg/amp
1 ampule,
Dexamethasone 5 mg/amp
cetirizine 10 mg 7 tabs,
and prednisolone 5 mg 20 tabs
Active Comparator Drug,Active Comparator Drug,Active Comparator Drug
CPM IV + Zyrtec po,CPM IV + Dexa IV + Zyrtec po,CPM IV + Dexa IV + Zyrtec po + prednisolone po
Sponsors
Rachada
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: Patients visit emergency room at King chulalongkorn memorial hospital (KCMH) age between 18-50 years who meet the following criteria of acute urticarial such as 1. eruption of wheals, central swelling of various sizes, with or without surrounding erythema; with or without angioedema 2. pruritus or occasional burning sensation 3. skin returning to normal appearance, usually within 1-24 hours
Exclusion criteria
Exclusion criteria: 1. patients who have urticarial for more than 48 hours 2. have severe underlying disease such as heart disease, kidney disease, liver disease 3. pregnancy 4. history of CPM, steroid, antihistamines allergy 5. history of antihistamine or steroid uses within 48 hours before ED visit 6. diabetes mellitus 7. suspected of more severe disease or severe allergic reaction 8. patients who don’t have puritus 9. patients who have history of chronic urticaria
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Itch score 60 minutes visual analog scale | — |
Secondary
| Measure | Time frame |
|---|---|
| Recurrent rash 1 week Binary outcome | — |
Countries
Thailand
Contacts
Public ContactPakhawadee Palungwachira
Chulalongkorn hospital
Outcome results
None listed