Trehalase enzymes are important for the growth and virulence of Aspergillus flavus

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

TCTR

Registry ID

TCTR20180316003

Enrollment

Registered

2018-03-16

Start date

2018-04-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

&#45

Interventions

The growth of clinical&#45

isolated Aspergillus flavus was measured in the presence of validamycin A compared to the wild type. The inhibitory effects of the combination of validamycin A and antifungal agents will also be eval

Experimental Other

Validamycin A group

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: - Clinical-isolated Aspergillus flavus 20 isolates

Exclusion criteria

Exclusion criteria: - other Aspergillus species

Design outcomes

Primary

Measure	Time frame
Inhibitory effects of validamycin A 1 year Minimal Inhibitory Concentration	—

Secondary

Measure	Time frame
Synergistic effects between validamycin A and antifungal agents 1 year Minimal inhibitory concentration and FIC	—

Countries

Thailand

Contacts

Public ContactArsa Thammahong

Faculty of Medicine, Chulalongkorn University

mee009@gmail.com022564132

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026