Comparison of Fractional Neodymiun-doped Yttrium Aluminium Garnet (Nd:YAG) 1,064-nm Picosecond Laser and Fractional 1,550-nm Erbium Fiber Laser in Facial Acne Scar Treatment

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

TCTR

Registry ID

TCTR20180307002

Enrollment

Registered

2018-03-07

Start date

2017-12-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Facial acne scar Acne scar Picosecond laser Erbium fiber laser

Interventions

Each patient would be randomly allocated one side of their faces to the group treated with fractional 1&#44

064&#45

nm Nd:YAG picosecond laser. The allocated side will be treated once a month for 4 months and then follow&#45

up every month for 2 months. At every visit&#44

before treatment&#44

photography will be taken with Visia. Side effects will be assessed at each visit.,Each patient would be randomly allocated one side of their faces to the group treated with fractional 1&#44

550&#45

nm erbium fiber laser. The allocated side will be treated once a month for 4 months and then follow&#45

photography will be taken with Visia. Side effects will be assessed at each visit.

Experimental Device,Active Comparator Device

Fractional 1&#44

nm Nd:YAG picosecond laser,Fractional 1&#44

nm erbium fiber laser

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: - Having diagnosed with facial atrophic acne scar by Dermatologist - Able to comply with treatment regulations and able to attend appointments assigned

Exclusion criteria

Exclusion criteria: - Having photosensitive dermatoses - Have been using photosensitising drugs - Having active acne vulgaris of the face - Having a history of keloid - Immunocompromised individual - Underwent laser treatment of the face within 3 months - Underwent chemical peeling of the face within 1 month - Taking or have taken oral vitamin A derivatives within 3 months - Using or have used topical vitamin A derivatives within 2 weeks - Having recurrent herpes infection - Pregnant or lactating women - Having a history of skin cancer - Having a history of allergy to any coal tar derivatives

Design outcomes

Primary

Measure	Time frame
Improvement score At 1, 2, 3, 4, 5 and 6 months Dermatologist evaluation of improvement in acne scar after each treatment	—

Secondary

Measure	Time frame
Side effect occurance At 1, 2, 3, 4, 5 and 6 months Dermatologist evaluation and patients' feedback,Pain score Immediately after each treatment Patients' feedback through 10-point scale	—

Contacts

Public ContactKorn Triyangkulsri

Division of Dermatology, Department of medicine, Faculty of Medicine, Ramathibodi hospital

korn.triy@gmail.com662011166

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026

Comparison of Fractional Neodymiun&#45;doped Yttrium Aluminium Garnet (Nd:YAG) 1&#44;064&#45;nm Picosecond Laser and Fractional 1&#44;550&#45;nm Erbium Fiber Laser in Facial Acne Scar Treatment