Clinical activity score Graves'
Conditions
Interventions
The selenium supplementation with a daily dose of 70 micrograms one capsule per oral in the morning for 6 months.,The selenium supplementation with a daily dose of 200 micrograms one capsule per oral
Placebo Comparator Dietary Supplement,Placebo Comparator Dietary Supplement,Sham Comparator Dietary Supplement
70 Selenium supplementation,200 Selenium supplementation,Placebo
Sponsors
Ratchadapiseksompotch Research fund
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: - Mild thyroid eye disease group according to EUGOGO recommendation - Age above 18 years old - Normal thyroid hormone level (FT4, FT3) for at least 6 months - Thyroid eye symptoms less than 24 months
Exclusion criteria
Exclusion criteria: - Allergic reaction to selenium - History of selenium use - Pregnant or breast-feeding - Recent history of orbital and eyelid surgery of less than 6 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Graves clinical activity score 0,6 months EUGOGO Graves clinical activity scaling | — |
Secondary
| Measure | Time frame |
|---|---|
| Graves' Quality of life 0,3,6 months Graves' Quality of life Questionaire | — |
Countries
Thailand
Contacts
Public ContactPreamjit Saonanon
Ophthalmology department, Chulalongkorn hospital
Outcome results
None listed