type 2 diabetes type 2 diabetes fat utilization immune function oxidative stress
Conditions
Interventions
Patient is this group start with 1000 mg of vitamin C supplement for 6 weeks then wash out for 6 weeks after that got placebo for 6 weeks,Patient is this group start with placebo for 6 weeks then wash
Active Comparator Dietary Supplement,Placebo Comparator Dietary Supplement
CB,PLA
Sponsors
Blackmores
Exercise and Sport Sciences Development and Research Group
Eligibility
Sex/Gender
All
Age
45 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Age between 45 and 60 years old 2. Being diagnosed as type 2 diabetes mellitus for at least 12 months 3. Hemoglobin A1c more than 8.5% 4. Being treated with oral diabetic drugs only 5. Sedentary and will not participate in any regular exercise program for at least 6 months. 6. Live in Khon Kaen Province, Thailand 7. Vessel state waveform less than level 5
Exclusion criteria
Exclusion criteria: 1. Cardiovascular disease and hypertension 2. Vessel state wave form more than level 5 3. Abnormal resting EKG 4. Blood pressure more than 140/90 mmHg. 5. Orthopedic problems or bone fracture 6. Neuromuscular disorder 7. Liver and kidney disease 8. Chronic infections 9. Autonomic neuropathy 10.VO2,peak less than 10 ml/kg/min
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| metabolism status visit 2,3,5,6 Expired gas collection, miR expression,oxidative stress status visit 2,3,5,6 Blood chem,white blood cell count visit 2,3,5,6 flow cytometry | — |
Secondary
| Measure | Time frame |
|---|---|
| N/A N/A N/A | — |
Countries
Thailand
Contacts
Public ContactChongchira Boonthongkaew
Khonkaen university
Outcome results
None listed