The effect of low dose intravenous lidocaine premedication on fentanyl induced cough in general anesthesia

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

TCTR

Registry ID

TCTR20180221002

Enrollment

Unknown

Registered

2018-02-21

Start date

2018-02-15

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

fentanyl induced cough fentanyl induced cough&#44

Interventions

0.25 mg/kg intravenous lidocaine premedication, 0.5mg/kg intravenous lidocaine premedication

intravenous lidocaine 0.25 mg/kg premedication before fentanyl injection in general anesthesia, intravenous lidocaine 0.5 mg/kg premedication before fentanyl injection in general anesthesia

Active Comparator Drug,Sham Comparator Drug

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Aged 18-60 years plan general anesthesia with endotracheal tube for surgery ASA 1-2 understand in Thai language

Exclusion criteria

Exclusion criteria: refused consent allergic to lidocaine preexisting of liver and kidney disease problem of language barrier history of asthma and COPD history upper respiratory tract infection in 2 week history taking of ACEI

Design outcomes

Primary

Measure	Time frame
cough score 12 month The degree of cough was defined by severity in mild, moderate, severe	—

Secondary

Measure	Time frame
none none none	—

Countries

Thailand

Contacts

Public ContactSithapan Munjupong

Phramongkutklao Hospital

sithapan@gmail.com0841153691

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026