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Motor-Sparing Effect of iPACK (Interspace Between the Popliteal Artery and Capsule of the Posterior Knee) Block versus Tibial Nerve Block after Total Knee Arthroplasty – a Randomized Controlled Trial

A Comparison of The motor-sparing effect between Interspace between The Popliteal Artery and The Capsule of The Posterior Knee block and Tibial Nerve Block Under Ultrasound-guidance in Enhanced Recovery for Total Knee Arthroplasty: A Randomized contr

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
TCTR
Registry ID
TCTR20180206002
Enrollment
105
Registered
2018-02-06
Start date
2018-02-09
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Total Knee Arthroplasty Total knee arthroplasty Tibial nerve block Popliteal plexus block Infiltration between popliteal artery and posterior capsule of the knee Continuous Adductor canal block

Interventions

guided single shot tibial nerve block was performed by injecting of 0.25% levobupivacaine 10 ml.,Ultrasound&#45
guided single shot infiltration between popliteal artery and posterior capsule of the knee was performed by injecting of 0.25% levobupivacaine 20 ml and adrenaline (1:200&#44
000).,Ultrasound&#45
000).
Tibial Nerve Block,upper iPACK,lower iPACK

Sponsors

none
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 79 Years

Inclusion criteria

Inclusion criteria: Patient who was scheduled for total knee arthroplasty at King Chulalongkorn Memorial Hospital ASA class 1 to 3 ASA class 1 A normal healthy patient. ASA class 2 A patient with mild systemic disease Mild diseases only without substantive functional limitations. ASA class 3 A patient with severe systemic disease but not threaten to life. Body mass index (BMI) between 18 to 40 kg/m2

Exclusion criteria

Exclusion criteria: refuse to participate this study allergy to any drug in this study contraindication to neuraxial anesthesia eg.coagulopathy contraindication to NSAIDs (Dynastat and Celebrex in this study) chronic opioids use or diagnosed of neuropathic pain unable to performed Time up and go test

Design outcomes

Primary

MeasureTime frame
common peroneal nerve motor blockade Preoperative and Postoperative 24 hours Rehabilitation after surgery,Posterior knee pain Pre op, Post op day0/1/2 Visual Analog Scale

Secondary

MeasureTime frame
Sensory and Motor Function of Tibial Nerve Postoperative 6 hours Plantar Flexion and Cold Sensation at Plantar aspect,Sensory and Motor Function of Common Peroneal Nerve Postoperative 6 hours Dorsiflexion and Cold Sensation at Dorsum aspect (included area between great and second toe,Postoperative Morphine Consumption Postoperative 12, 24 and 48 hours Milligram of Morphine Consumption,Postoperative Pain Score Postoperative 0, 0.5, 1, 2, 4, 8, 12, 24, 36, 48 and 60 hours, 2 weeks, 6 weeks, 12 weeks Visual Analog Scale,Quadriceps Strength Postoperative 0, 1, 2, 3 Days and 3 Months Maximum voluntary isometric contraction,Cumulated Ambulation Score Postoperative 0, 1, 2, 3 Days Rehabilitation after surgery,Postoperative Complication Postoperative 0, 1, 2, 3 Days Postoperative Nausea Vomiting, Fall, Sleep disturbance,Timed up and go test Postoperative 3 Months Rehabilitation after surgery,Degree of knee flexion (active and passive) Postoperative 0, 1, 2, 3 Days and 3 Months Degree of range of motion

Countries

Thailand

Contacts

Public ContactWirinaree Kampitak

Faculty of medicine, Chulalongkorn University

nutong127@yahoo.com6689-9955-666

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Apr 4, 2026