Effect of intraoperative liberal fluid therapy on postoperative nausea and vomiting in preschool children undergoing laparoscopic lower abdominal surgery:A radomized controlled trial

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

TCTR

Registry ID

TCTR20180126002

Enrollment

Unknown

Registered

2018-01-26

Start date

2018-03-01

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

post operatiev vomiting in preschool children postoperative nausea and vomiting laparoscopic surgery liberal fluid therapy pediatric anesthesia

Interventions

Loading with acetate ringer solution 30 ml/kg intravenous in first hour of anesthetic period. Second and more consecutive hour&#44

Administrate acetate ringer solution in maintenace rate (Holiday&#45

Segar&#44

4&#45

2&#45

1 rule),Loading with acetate ringer solution 10 ml/kg intravenous in first hour of anesthetic period. Second and more consecutive hour&#44

1 rule)

Experimental Drug,Active Comparator Drug

acetate ringer solution 30 ml/kg/hr,acetate ringer solution 10ml/kg/hr

Eligibility

Sex/Gender

All

Age

1 Years to 6 Years

Inclusion criteria

Inclusion criteria: - ASA I,ASAII - Age 1-6 years old - Undergoing laparoscopic lowerabdominal surgery (laparoscopic herniotomy,laparoscopic diagnosis and/or orchidoplexy,laparoscopic repair hydrocele)

Exclusion criteria

Exclusion criteria: -Weight for age > 97 percentile -Administrated antiemitic drugs or antipsychotic drugs in 24 hours before surgery -Gastroesophageal reflux disease -Cardiovascular diseas/ Renal disease -Anticipated difficult airway -Caregiver refusal

Design outcomes

Primary

Measure	Time frame
Incidences of post operative nausea and vomiting 24 hours percentage	—

Secondary

Measure	Time frame
Incidences of congestive heart failure/pulmonary edema 24hours percentage,Incidences of peripheral edema 24 hours percentage	—

Countries

Thailand

Contacts

Public ContactPariya Plicharoenpon

Department of anesthesia

p.pariya@gmail.com0818802218

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Apr 4, 2026