Comparison of magnesium sulphate protocol by weight-adjusted versus 2 grams per hour for preventing convulsion in preeclampsia: a randomized trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20180122001

Enrollment

Registered

2018-01-22

Start date

2018-01-22

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

preeclamsia with severe feature preelampsia magnesium sulfate

Interventions

magnesium sulfate maintenance infusion 2 g/hr after loading dose magnesium sulfate 4 g,magnesium sulfate maintenance infusion 1.2&#44

1.3&#44

1.4&#44

1.5 g/hr if BW /=100 after loading dose magnesium sulfate 4 g

Active Comparator Drug,Experimental Drug

magnesium sulfate maintenance infusion 2 g/hr,magnesium sulfate maintenance infusion weight related dose

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: pregnant woman with preelampsia with severe feature , gestational age > 24 wks

Exclusion criteria

Exclusion criteria: serum creatinine >1.3 urine output < 25 ml/hr hypersensitivity myocardial damage diabetic coma heart block myastinia gravis

Design outcomes

Primary

Measure	Time frame
serum magnesium level after magnesium sulfate infusion 2,4 hr blood for serum magnesium level after maintenance dose (therapeutic level 4.8-8.4)	—

Secondary

Measure	Time frame
maternal and neonatal outcome all time observe maternal and neonatal complication form mgso4	—

Countries

thailand

Contacts

Public Contactrawisara champawong

udonthani hospital

neen_51@hotmail.com+66885718661

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026

Comparison of magnesium sulphate protocol by weight&#45;adjusted versus 2 grams per hour for preventing convulsion in preeclampsia: a randomized trial