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Generic Latanoprost: An Equivalent Comparison Open-labelled Study

Intra-ocular pressure reduction efficacy and safety of generic latanoprost marketed in Thailand after switching from the original: a randomized open-labelled controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
TCTR
Registry ID
TCTR20180115001
Enrollment
70
Registered
2018-01-15
Start date
2018-05-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glaucoma Ocular hypertension Currently using original latanoprost Glaucoma Ocular hypertention Prostaglandins analogue Latanoprost Generic drug Intraocular pressure

Interventions

Original latanoprost (Xalatan),Generic latanoprost 1 (Lanotan),Generic latanoprost 2 (Mylan)
Active Comparator Drug,Active Comparator Drug,Active Comparator Drug
Original,Generic 1,Generic 2

Sponsors

Bausch & Lomb Co., Ltd.
Lead Sponsor
Atlanta Medicare Co.&#44
Collaborator
Ltd.
Collaborator

Eligibility

Sex/Gender
All
Age
20 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients who have been diagnosed with any type of glaucoma or ocular hypertension No history of cataract within the last 3 months Using the original latanoprost (Xalatan) for more than 4 weeks

Exclusion criteria

Exclusion criteria: History of any type of intraocular pressure reduction surgery History of laser peripheral iridotomy within the last 3 months History of ocular trauma Currently on more than 1 antihypertensive eyedrops apart from latanoprost History of any irregular ocular surface condition Currently on glucocorticoid eyedrops

Design outcomes

Primary

MeasureTime frame
Intraocular pressure reduction at 4 and 12 week after start the intervention Goldmann applanation tonometer

Secondary

MeasureTime frame
Safety at 4 and 12 week after start the intervention Physical examination, patients' comment

Contacts

Public ContactNuntachai Surawatsatien

King Chulalongkorn Memorial Hospital

nuntachais@gmail.com+6687-111-5599

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026