Patients with a diagnosis of chronic obstructive pulmonary disease (COPD) stage I,
Conditions
Interventions
After day 1,
the participant completely perform incremental work rate SMT.
on day two,
the participants will randomly be assigned to among the difference two work rate SMT including constant work rate SMT,
paced work rate SMT by random block allocation. if the participants will randomized to constant work rate SMT first. After that,
the participants will rest at least 1 hour for wash out period and heart rate retuned to baseline and Rating of perceived breathlessness and Rating of perceive of arm and leg exertion score will be 0
they will perform the self-
paced work rate SMT last. Finally,
the data of participants who complete the study will be analysis.,After day 1,
paced work rate SMT by random block allocation. if the participants will randomized to self-
paced work rate SMT first. After that,
they will perform the constant work rate SMT last. Finally,
the data of participants who complete the study will be analysis.
Experimental Other,Experimental Other
track one,track two
Sponsors
the faculty of associated medical science
the cardiopulmonary research laboratory
Eligibility
Sex/Gender
All
Age
35 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) Age at 35-80 years old, both male and female 2) Good cooperative and well communication. 3) Clinical stable free form exacerbation at four week before enroll to study. 4) Independent from home oxygen therapy. 5) Stable vital signs 6) Independent walking without walking aid.
Exclusion criteria
Exclusion criteria: 1) Cardiovascular system contraindication for exercise testing including significant resting ECG suggesting ischemia, recent myocardial infarction, or cardiac event, unstable angina, uncontrolled dysrhythmias causing symptoms or hemodynamic compromise and symptomatic heart failure, symptomatic severe aortic stenosis, acute myocarditis or pericarditis, and suspected or known dissecting aneurysm. 2) Resting systolic blood pressure > 160 mmHg and/or diastolic blood pressure > 100 mmHg. 3) Chronic kidney disease; end stage renal disease 4) Uncontrolled diabetes mellitus 5) Pulmonary hypertension, pulmonary edema, pulmonary embolus, pneumonia, and tuberculosis. 6) Oxygen saturation at room air < 90% 7) Musculoskeletal problem including frozen shoulder, hip or knee osteoarthritis, hip or knee arthroplasty, back pain affecting walking or marching, and disability of upper or lower limb. 8) Impairment of visual, vesicular, and hearing function that affect their balance. 9) Body mass index more than 30 kg/m2
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| peak oxygen consumption every minute expired gases analyzer | — |
Secondary
| Measure | Time frame |
|---|---|
| Carbon dioxide output every minute expired gases analyzer,Metabolic equivalent every minute expired gases analyzer,Respiratory exchange ratio every minute expired gases analyzer,Respiratory rate every minute expired gases analyzer,Tidal Volume every minute expired gases analyzer,Minute Ventilation every minute expired gases analyzer,End-tidal Partial Pressure of oxygen every minute expired gases analyzer,End-tidal Partial Pressure of carbon dioxide every minute expired gases analyzer,The ventilatory equivalent for oxygen every minute expired gases analyzer,The ventilatory equivalent for carbon dioxide every minute expired gases analyzer,oxygen saturation every minute pulse oximeter,Heart rate every minute Portable bedside monitor,systolic blood pressure start resting, start baseline, immediate pre-exercise, end exercise, every 2 min in recovery phase Portable bedside monitor,diastolic blood pressure start resting, start baseline, immediate pre-exercise, end exercise, every 2 min in recovery phase Portable bedside monitor,mean arterial pressure start resting, start baseline, immediate pre-exercise, end exercise, every 2 min in recovery phase calculation by systolic and diastolic blood pressure,Rating of perceived breathlessness every minute Modified Borg Scale ,Rating of perceive of arm exertion every minute Modified Borg Scale ,Rating of perceive of arm every minute Modified Borg Scale ,Rating of perceive of leg every minute Modified Borg Scale ,blood lactate concentration immediate pre-exercise and immediate end exercise blood sample from the tip of finger 5 microliter,step count during exercise time pedometer,gender recruitment asking the participant,age recruiment asking the participant,ideal body weight recruiment assessment,hight recruiment assessment,medical diagnosis recruiment diagnosis by the doctor,underlying recruiment asking the participant and medical history,pulmonary func | — |
Countries
Thailand
Contacts
Public ContactJirawat Limphatcharaporn
Cardiopulmonary research labolatory, Faculty of Associated Medical Sciences, Khon Kaen University.
Outcome results
None listed