Effects of high frequency repetitive transcranial magnetic stimulation and sertraline on depressive symptoms in patients after ischemic stroke

Effects of High Frequency Repetitive Transcranial Magnetic Stimulation and Sertraline on Depressive Symptoms in Patients after Ischemic Stroke

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20180112001

Enrollment

Unknown

Registered

2018-01-12

Start date

2014-04-01

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post stroke depression Repetitive transcranial magnetic stimulation Antidepressant Post stroke depression

Interventions

10&#45

Hz repetitive transcranial magnetic stimulation,50 mg of Sertraline,10&#45

Hz repetitive transcranial magnetic stimulation and 50 mg of Sertraline

Experimental Device,Active Comparator Drug,Experimental Other

rTMS,Antidepressant,Combined rTMS and antidepressant

Eligibility

Sex/Gender

All

Age

18 Years to 0 Years

Inclusion criteria

Inclusion criteria: -Ischemic stroke patients -Age 18 years or more -Have depressive symptoms (diagnosed with DSM-IV-TR) -No antidepressant taken

Exclusion criteria

Exclusion criteria: -Have other neurological diseases -Had depression prior to stroke -Had seizure, epilepsy or history of head trauma -Have pacemaker or metallic implant inside the brain -Inability to communicate -Thai Mental State Examination (TMSE) score less than 23

Design outcomes

Primary

Measure	Time frame
17-item Hamilton rating scale for depression Thai version (THAI HRS-D 17) 0, 2nd, 6th and 14th week Assessment form	—

Secondary

Measure	Time frame
Modified Barthel Index 0, 2nd, 6th and 14th week Assessment form,Brunnstrom stages of stroke recovery 0, 2nd, 6th and 14th week Assessment form,Adverse effects All time Medical record, interview	—

Countries

Thailand

Contacts

Public ContactPim Terachinda

Department of Rehabilitation Medicine Chulalongkorn University

pim_bh@yahoo.com0898318773

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Apr 4, 2026