Parkinson'
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: diagnosed idiopathic PD according to the United Kingdom Brain Bank Criteria with Hoehn and Yahr stages 1 – 3,aged at least 50 years of old, stable on anti-PD medications, and could walk 10m with or without any walking assist
Exclusion criteria
Exclusion criteria: -musculoskeletal or cardiopulmonary disorders -undergone neurosurgery -neurologic conditions other than PD -showed cognitive deficits on the Mini-Mental State Examination (<24) -joined another exercise program in the previous 3 months -met the criteria for exclusion for the use of TMS (i.e. metal implants, cardiac pacemaker, history of epilepsy, previous brain injury, actively taking antidepressant drugs)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cortical excitability measured before the training, after the training and one-month follow-up measured by transcranial magnetic stimulation(TMS) using a double-cone coil | — |
Secondary
| Measure | Time frame |
|---|---|
| Balance measured before the training, after the training and one-month follow-up assessed by using the Mini-Balance Evaluation Systems Test (Mini-BESTest),Cognition measured before the training, after the training and one-month follow-up measured by the Montreal Cognitive Assessment (MoCA),Cognition measured before the training, after the training and one-month follow-up measured by the Chinese version of Trail Making Test (TMT) ,Cognition measured before the training, after the training and one-month follow-up measured by the Digit Span Task (DST),Quality of life measured before the training, after the training and one-month follow-up measured by the Chinese version of the Parkinson's Disease Questionnaire (PDQ-39) | — |
Countries
Taiwan (ROC)
Contacts
National Yang Ming University