Comparison of different mouthrinses

Effects of Chlorine Dioxide and Chlorhexidine on the Prevention of Alveolar Osteitis: Double-Blinded, Randomized, Clinical, Controlled Study

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

TCTR

Registry ID

TCTR20180110001

Enrollment

300

Registered

2018-01-10

Start date

2018-01-09

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients in good general health condition who have at least 1 third molar with full mucosal retention that needed to be extracted. chlorhexidine gluconate&#44

Interventions

patients will use the chlorhexidine mouth rinse 24 hours after extraction&#44

3 times a day for one week,patients will use the chlorine dioxide mouth rinse 24 hours after extraction&#44

3 times a day for one week,patients will use the distilled water mouth rinse 24 hours after extraction&#44

3 times a day for one week

Active Comparator Other,Experimental Other,Placebo Comparator Other

Chlorhexidine mouth rinse,Chlorine dioxide mouth rinse,Distilled water

Eligibility

Sex/Gender

All

Age

18 Years to 38 Years

Inclusion criteria

Inclusion criteria: 1. Patients with regular tooth brushing habit twice a day 2. non-smokers

Exclusion criteria

Exclusion criteria: 1. Patients with pericoronitis or taking antibiotics for other infections within the last 6 months 2. Patients using anti-inflammatory drugs within the last 3 months 3. Pregnancy and breast-feeding 4. Use of hormone contraceptives 5. Smoking

Design outcomes

Primary

Measure	Time frame
Pain 3 and 7 days after extraction Visual Analog Scale	—

Secondary

Measure	Time frame
Difficulties of insemination method 2 minutes Scale 1-10	—

Countries

TURKEY

Contacts

Public ContactGizem Ince Kuka

Yeditepe University

gizemince@icloud.com00905308243499

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026