Ischemic heart disease (patients undergoing CABG) postoperative pain,
Conditions
Interventions
0.15mg / kg of methadone ,0.1mg / kg of morphine
Active Comparator Drug,Active Comparator Drug
Sponsors
shahid sadoughi university of medical sciences
shahid sadoughi university of medical sciences,shahid sadoughi university of medical sciences
Eligibility
Sex/Gender
All
Age
0 Years to 90 Years
Inclusion criteria
Inclusion criteria: 76 opiate-addicted patients with ASA class II and III, aged < 90 years undergoing CABG
Exclusion criteria
Exclusion criteria: history of preoperative renal failure requiring hemodialysis or serum creatinine greater than 2mg / dl, severe hepatic failure, EF less than 30%, pulmonary disease requiring oxygen therapy at home, a disease requiring the use of inotropes or intra-aortic pumps, emergency surgeries and allergy to methadone or intravenous morphine
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| mean pain scores At ICU admission 1 hour after ICU admission 2 hours after ICU admission 3 RASS and BPS score,nausia after the operation Questionnaire,vomiting after the operation Questionnaire | — |
Secondary
| Measure | Time frame |
|---|---|
| Hemodynamic variables ( MAP, O2SAT, HR) at the time of ICU admission, 1, 2, 3, and 4 hours after the operation, and 30 minutes and 2 hours a manomerty, pulse oxymetery, ECG | — |
Countries
Iran
Contacts
Public ContactHossein Moshtaghion
Shahid Sadoughi university of medical sciences,Yazd, Iran
Outcome results
None listed