End stage kidney disease Receiving twice or thrice weekly hemodialysis hemodialysis, elderly, incremental dialysis, kidney failure, end stage kidney disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age 65 years or older 2. Have been diagnosed with end stage renal disease 3. Receving twice or thrice weekly hemodialysis regularly at Bhumirajanakarindra Kidney Institute Hospital at least 3 months before enrollment 3. Signed written informed consent approved by the Ethical Review Committee for Research in Human Subjects, Ministry of Public Health
Exclusion criteria
Exclusion criteria: History of previous peritoneal dialysis or kidney transplantation Patients who did not give written informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| composite end points of all-cause mortality, cardiovascular events, hospitalization from any cause 36 months rate/patient-year | — |
Secondary
| Measure | Time frame |
|---|---|
| All-cause mortality 36 months rate/patient-year,Death from cardiovascular cause 36 months rate/patient-year,Cardiovascular events 36 months rate/patient-year,Hospitalization from any infection 36 months rate/patient-year,Hospitalization from cardiovascular events 36 months rate/patient-year,Health related quality of life every 6 months KDQOL-36 score (Thai version),Caregiver burden every 6 months Scale by Zarit Burden Interview (Thai version),Residual renal function every 6 months Kr (ml/min/1.73m2), urine volume (ml),Adequacy of hemodialysis every 6 months stdKt/V per week,Nutritional status every 6 months nPCR, serum albumin (g/dL),Markers of metabolic bone disease every 6 months Serum calcium (mg/dL), phosphate (mg/dL), parathyroid hormone (pg/mL),Anemia every 6 months Hb (g/dL), ESA dose (units/week),Vascular access complication 36 months rate/patient-year,Vascular access complication 36 months rate/patient-year | — |
Countries
Thailand
Contacts
Bhumirajanakarindra Kidney Institute Hospital