abdominal striae distensae
Conditions
Interventions
The first section of abdominal striae is treated with pneumatic needleless micro-
jet injector with diluted hyaluronic acid filler.,The second section is treated with pneumatic needleless micro-
jet injector with normal saline solution.,The third section is left untreated to serve as control arm.
pneumatic needleless micro-
jet injector with hyaluronic acid filler,pneumatic needleless micro-
jet injector with normal saline,untreated
Sponsors
Division of Dermatology, Department of Medicine, Faculty of Medicine, Mahidol University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. age of 18 years or older 2. having stable striae distensae on lower abdominal area without change for at least 6 months 3. willing to return for every required follow-up visits 4. capacity to giving written informed consent
Exclusion criteria
Exclusion criteria: 1. pregnancy and lactation 2. history of allergy to hyaluronic acid, fillers, or local anesthesia 3. having topical drugs, injectables, devices, or surgery 1 year prior to recruitment 4. history of tanning within 1 month 5. history of connective tissue disease or keloid 6. having infection, dermatitis, skin cancer, or abnormal skin condition in treatment area 7. immunocompromised host 8. taking isotretinoin 1 year prior to recruitment 9. unable to follow the protocol
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Physician assesment week 0, 4, 8, 20, 32 visual analog scale of color, texture, degree of atrophy | — |
Secondary
| Measure | Time frame |
|---|---|
| Histopathological assessment week 0, 8 evaluation of dermal collagen and elastin | — |
Countries
Thailand
Contacts
Public ContactSalinee Rojhirunsakool
Nil
Outcome results
None listed