chronic spinal cord injury neuropathic pain chronic spinal cord injury neuropathic pain
Conditions
Interventions
tDCS,
upper body exercise
Participants in both groups will receive tDCS followed by upper body exercises 3 sessions a week for 4 weeks.
we will apply anodal transcranial direct current stimulation (tDCS) over C3 or C4 (EEG 10/
and cathodal electrode over the contralateral supraorbital area as a reference. A constant current of 2 mA will be applied for 20 mins in experimental group.
upper body exercise will includes 25 minu
25 minutes of resistance exercise plus 5 minutes of stretching. The intensity of arm ergometry exercise will be set at “12-
13†(somewhat hard) in rating of perceived exertion (RPE).,sham tDCS,
upper body exercise
The control group will receive stimulation for the first 15 secs.
upper body exercise program will be the same as in the experimental group.
Experimental Device,Sham Comparator Device
anodal transcranial direct stimulation (tDCS) followed by upper body exercise,sham anodal transcranial direct stimulation followed by upper body exercise
Sponsors
National Yang Ming University
Taipei Veterans General Hospital,
Taiwan
Eligibility
Sex/Gender
All
Age
20 Years to No maximum
Inclusion criteria
Inclusion criteria: (1) having diagnosis of SCI-associated neuropathic pain (NP), (2) having NP symptoms for more than 6 months, (3) intensity of NP greater than 4 / 10 indicated by numeric rating scale (NRS), (4) under other analgesic treatments for 3 months but not receiving satisfied effect, and (5) willing and consent to participate the study.
Exclusion criteria
Exclusion criteria: (1) unstable medical condition, (2) unable to participate in exercise programs due to other diseases or lesions, (3) had or has drug addiction problems, (4) participating in other clinical trial in previous month, (5) history of epilepsy, underwent brain surgery, meningitis, encephalitis, and intracranial space occupied lesion, (6) has a cardiac pacemaker, (7) undergoing pregnancy or lactation, (8) any kind of metal or other implant in brain or head, (9) pathological changes over skin of stimulation sites
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| pain intensity before (pre-test), immediately after the test (post-test), and 4-week follow-up (follow-up test). numeric rating scale (NRS) | — |
Secondary
| Measure | Time frame |
|---|---|
| character of NP before (pre-test), immediately after the test (post-test), and 4-week follow-up (follow-up test). Neuropathic Pain Symptom Inventory (NPSI) ,Self-rating change of pain immediately after the test (post-test), and 4-week follow-up (follow-up test). patient global impression of change (PGIC),Quality of life before (pre-test), immediately after the test (post-test), and 4-week follow-up (follow-up test). Chinese Version of International Spinal Cord Injury Quality of Life Basic Data Set Version 1.0 (SCIQ,Brain wave activity before (pre-test), immediately after the test (post-test), and 4-week follow-up (follow-up test). resting electroencephalography (EEG) with eyes closed | — |
Countries
Taiwan
Contacts
Public ContactRay-Yau Wang
Department of Physical therapy and Assistive Technology, National Yang Ming University
Outcome results
None listed