Efficacy of lidocaine spray in pain reduction during colposcopy-directed cervical biopsy: a randomized controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

TCTR

Registry ID

TCTR20171208001

Enrollment

360

Registered

2017-12-08

Start date

2017-12-12

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Women with abnormal cervical cytology (ASC&#45

Interventions

10% lidocaine spray,Normal saline,No intervention

Experimental Drug,Placebo Comparator No treatment,No Intervention No treatment

Eligibility

Sex/Gender

Female

Age

20 Years to No maximum

Inclusion criteria

Inclusion criteria: Women with abnormal cervical screening test results and abnormal colposcopic findings that required a colposcopic directed biopsy.

Exclusion criteria

Exclusion criteria: 1.Known history of hypersensitivity to lidocaine or to other components of the solution 2.Pregnancy 3.Post-hysterectomy 4.Bleeding disorders 5.Drug abuse 6.Cervical and vaginal infection 7.Inability to communicate in Thai.

Design outcomes

Primary

Measure	Time frame
Biopsy pain score. 2 minutes after apply 10% Lidocaine spray Visual analog scale	—

Secondary

Measure	Time frame
N/A N/A N/A	—

Countries

Thailand

Contacts

Public ContactCharuwan Saeteng

Chiang Mai University

nokctantipa@gmail.com083-7629929

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026

Efficacy of lidocaine spray in pain reduction during colposcopy&#45;directed cervical biopsy: a randomized controlled trial