Eyebrow hypotrichosis eyebrow hypotrichosis
Conditions
Interventions
0.01% Bimatoprost was proved to be effective in the treatment of eyebrows hypotrichosis in our latest study,0.03% Bimatoprost was proved to be effective in the treatment of eyebrows hypotrichosis in p
Experimental Drug,Active Comparator Drug
0.01% Bimatoprost,0.03% Bimatoprost
Sponsors
Division of Dermatology, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol U
Mahidol University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Patients with eyebrow hypotrichosis 2.Age more than 18 year-old 3.No serious underlying diseases 4.Informed consent 5.Compatible with follow-up schedule
Exclusion criteria
Exclusion criteria: 1.Patients undergone eyebrow transplantation 2.Previously treated with drugs or products affecting eyebrow cycle within 2 wks 3.Previously treated with minoxidil, systemic antiandrogen, topical estrogen/progesterone, topical prostaglandin analogs, anabolic steroids, lithium, phenothiazines 4.Patients with underlying diseases involving eyebrow hypotrichosis eg. Cancer, immunocompromised, thyroid diseases or psychiatric disorders including trichotillomania 5.Patients undergone eyebrow tattooing 6.Patients with history of poor wound healing or with skin pathology on eyebrow 7.Allergic to bimatoprost 8.Pregnancy or lactation 9.Withdraw
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The Global Eyebrow Assessment (GEBA) scale Week 0, Week 24 Photos taken with VISIA and evaluated by blinded dermatologists,Eyebrow hypotrichosis improvement Week 24 7-point rating scale by photos taken with VISIA and evaluated by blinded dermatologists and patients,Eyebrows density and diameter Week 0, Week 4, Week 8, Week 12, Week 16, Week 20, Week 24 Folliscope® (LeadM Corporation, Seoul, South Korea) | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse effects (eg. itchiness, erythema etc.) Week 0, Week 4, Week 8, Week 12, Week 16, Week 20, Week 24 Evaluated from patients and attending dermatologists,Patient satisfaction Week 24 Patients satisfaction rating score | — |
Countries
Thailand
Contacts
Public ContactSarawin Harnchoowong
Division of Dermatology, Faculty of Medicine Ramathibodi Hospital
Outcome results
None listed