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308-nm Excimer lamp therapy vs. combination of 308-nm excimer lamp therapy and 10% Liquor carbonis detergent (LCD) in patients with scalp psoriasis, a prospective, comparative study of efficacy and safety

308-nm Excimer lamp therapy vs. combination of 308-nm excimer lamp therapy and 10% Liquor carbonis detergent (LCD) in patients with scalp psoriasis, a prospective, comparative study of efficacy and safety

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
TCTR
Registry ID
TCTR20171128003
Enrollment
30
Registered
2017-11-28
Start date
2017-11-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Plaque&#45

Interventions

15 patients would be allocated to the group treated with 308&#45
nm Excimer lamp only. Starting energy for all patients is 500 mJ with increment of 10% each treatment. Treatment sessions are 2 times per week with a total of 20 sessions. (unless the lesions complete
such as severe pain or skin burn&#44
the treatment will be skipped on that day and resumed with lower energy on the next visit.,15 patients would be allocated to the group treated with 308&#45
nm Excimer lamp with 10% liquor carbonis detergens (LCD). Each patients will be given 10% LCD cream to apply for at least 5 hours then rinsed off the night before each treatment sessions. Starting ene
the treatment will be skipped on that day and resumed with lower energy on the next visit. If the side effect is thought to be from 10% LCD cream such as contact dermatitis or pain&#44
the patient will be exempted from further use of 10% LCD cream
Active Comparator Device,Experimental Device
308&#45
nm Excimer lamp only,308&#45
nm Excimer lamp with 10% liquor carbonis detergens

Sponsors

Division of Dermatology, Department of medicine, Faculty of Medicine, Ramathibodi hospital
Lead Sponsor
Mahidol University
Collaborator

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: - Having diagnosed with plaque-type psoriasis on the scalp by Dermatologist - Able to comply with treatment regulations and able to attend appointments assigned

Exclusion criteria

Exclusion criteria: - Having photosensitive dermatoses - Have been using photosensitising drugs - Having pustular type or erythrodermic type psoriasis - Pregnant or lactating women - Having a history of skin cancer - Having a history of allergy to any coal tar derivatives

Design outcomes

Primary

MeasureTime frame
PASI score After 20th treatment, after last treatment, 1 month after last treatment Dermatologist evaluation of severity of psoriasis based on given range of scores—

Secondary

MeasureTime frame
Side effect occurance Evaluate on every visit, 1 and 2 months after last treatment Dermatologist evaluation and patients' feedback—

Contacts

Public ContactPloysyne Rattanakaemakorn

Division of Dermatology, Department of medicine, Faculty of Medicine, Ramathibodi hospital

ploysyne@gmail.com662011166

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026