A Randomized Controlled Trial Comparing Effectiveness of 3% vs 30% NaCl Solution for Treatment of Umbilical Granuloma

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

TCTR

Registry ID

TCTR20171122004

Enrollment

100

Registered

2017-11-22

Start date

2017-12-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Umbilical granuloma umlilical granuloma

Interventions

Apply solution on umbilical granuloma three time a day until complete epithelialization,Apply solution on umbilical granuloma three time a day until complete epithelialization

Active Comparator Procedure/Surgery,Active Comparator Procedure/Surgery

3% NaCl solution,30% NaCl solution

Eligibility

Sex/Gender

All

Age

5 Days to 12 Months

Inclusion criteria

Inclusion criteria: All infants with umbilical granuloma

Exclusion criteria

Exclusion criteria: Exclusion criteria Infant with omphalitis Infant with umbilical polyp Infant with omphalomesenteric anomaly

Design outcomes

Primary

Measure	Time frame
Cure rate of treatment: completed epithelialization by hypertonic NaCl solutio within 3 week observation,Time to response within 3 week time in day	—

Secondary

Measure	Time frame
Possible side effect within 3 week observation	—

Countries

Thailand

Contacts

Public ContactPracha Nuntnarumit

Ramathibodi Hospital

pracha.nun@mahidol.ac.th0819475906

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026