The Optimal Temperature for Replacement Fluid and Dialysate in Continuous Renal Replacement therapy (CRRT): A randomized controlled study

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20171117001

Enrollment

Registered

2017-11-17

Start date

2017-06-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute kidney injury requiring continuous renal replacement therapy in ICU Continuous renal replacement therapy Acute kidney injury Dialysate temperature Replacement fluid temperature

Interventions

Set dialysate/replacement fluid temperature at 37.0 degree celsius ,Set dialysate/replacement fluid temperature at 35.5 degree celsius

Active Comparator Procedure/Surgery,Experimental Procedure/Surgery

Dialysate/Replacement fluid temperature at 37C,Dialysate/Replacement fluid temperature at 35.5C

Eligibility

Sex/Gender

All

Age

15 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patient age of more than 15 years 2. Patients who require continuous renal replacement therapy 3. Patients or relatives gave written informed consent

Exclusion criteria

Exclusion criteria: 1. Kidney transplant patients 2. Patients whom treated with slow continuous ultrafiltration (SCUF)

Design outcomes

Primary

Measure	Time frame
Stable hemodynamics 4 hours Blood pressure and norepinephrine dose	—

Secondary

Measure	Time frame
Stable hemodynamics 8 hours Blood pressure and norepinephrine dose,Blood lactate 8 hours Accusport, Roche Diagnostics,Death rate In hospital Percentage of patients who died	—

Countries

Thailand

Contacts

Public ContactKajohnsak Noppakun

Chiang Mai University

kajohnsak.noppakun@cmu.ac.th66-81-595-3465

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026