Systemically healthy moderate Chronic Periodontitis (CP) patients with radiographically detectable horizontal bone loss,
Conditions
Interventions
2*100 millions of L.reuteri containing probiotic dietary supplement tablets will be used twice a day for 3 weeks.,Identically same tablets without live bacteria will be used twice a day for a 3-
week period.
Active Comparator Dietary Supplement,Placebo Comparator Dietary Supplement
L.reuteri containing probiotic tablets, tablets without active ingridients
Sponsors
Yeditepe University Faculty of Dentistry
Marmara University Faculty of Dentistry,
Department of Basic Sciences
Eligibility
Sex/Gender
All
Age
35 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1) Systemically healthy moderate CP patients 2) Patients that have not received periodontal therapy or drugs that may effect periodontium prior 6 months to the study 4) Non-smokers 5) No regular use of probiotic dietary supplements
Exclusion criteria
Exclusion criteria: 1) Sampling teeth with prosthetic restorations 2) Pregnant or nursing mothers 3) Smokers or former smokers 4) Allergic reactions to lactose or fermented milk products
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gingival Crevicular Fluid Nitric Oxide Levels 3 months Griess colorimetric method | — |
Secondary
| Measure | Time frame |
|---|---|
| Gingival Crevicular Fluid Nitric Oxide Levels 6 months Griess colorimetric method | — |
Contacts
Public ContactGizem Kuka
Yeditepe University
Outcome results
None listed