bleb failure bleb hypervascularity Post-
Conditions
Interventions
topical Bevacizumab (instill 1 drops into eye up to 3 times every 4 hours) in post-
trabeculectomy case
other than topical 1%prednisolone acetate,topical normal saline (instill 1 drops into eye up to 3 times every 4 hours) in post-
trabeculectomy case
other than topical 1%prednisolone acetate
Experimental Procedure/Surgery,Placebo Comparator Procedure/Surgery
topical Bevacizumab,topical normal saline
Sponsors
Faculty of medicine,Khonkaen university
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: uncontrolled primary glaucoma and secondary glaucoma vascularity score of Würzburg bleb classification score (WBCS) of post-operative bleb is <2 and/or Corkscrew vessels score < 3 older than 18 years old
Exclusion criteria
Exclusion criteria: post-operative hypotony, wound leak, flat anterior chamber, suprachoroidal hemorrhage, choroidal detachment One eye condition neovascular glaucoma and uveitic glaucome Recent Myocardial infarction or Stroke During pregnancy or lactation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| proportion of patients with bleb that reduced its vascularization Post-operation : day 1,2,7 grading of the bleb by Würzburg bleb classification score (WBCS) | — |
Secondary
| Measure | Time frame |
|---|---|
| Complication, Success surgical outcome Post-operation : day 1,2,7 Observation of complication, Intraocular pressure measurement | — |
Contacts
Public ContactWatcharaporn Thongmee
Faculty of medicine, Khonkaen university
Outcome results
None listed