breast cancer breast cancer scalp cooling alopecia chemotherapy
Conditions
Interventions
Scalp cooling is applied for this arm in every cycle of chemotherapy at least 4 consecutive cycles. ,Scalp cooling is NOT applied for this arm in every cycle of chemotherapy at least 4 consecutive cyc
Scalp cooling,Scalp cooling
Sponsors
Ratchadapiseksompotch Fund (Pending)
Ratchadapiseksompotch Fund (Pending)
Eligibility
Sex/Gender
Female
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.Age 18-70 years old 2.CA breast patient who recieve one of the following chemotherapy regimen : oxorubicin cyclophosphamide or taxane-based regimen as neoadjuvant chemotherapy or adjuvant chemotherapy 3. At least 4 cycles of chemotherapy
Exclusion criteria
Exclusion criteria: 1. History of previous chemotherapy treatment 2. Alopecia at least gr.I before receiving chemotherapy 3. History of migraine, hypothyroid, hepatitis, uncontrolled diabetes, cold intolerance, cryoglobulinemia, cryofibrinogenemia or cold agglutinin disease 4. History of iron deficiency anemia 5. History of oral contraceptive pill or hormone replacement therpary 6. History of psychological disorder diagnosed by psychiatrist 7. History of scalp disease 8. History of previous alopecia treatmenr 9. History of hair transplantation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hair count after each chemotherapy cycle Hair scope | — |
Secondary
| Measure | Time frame |
|---|---|
| Hair mass index after each chemotherapy cycle HairCheck instrument,Breast Cancer-Specific Quality of Life Questionnaire Items after each chemotherapy cycle Questionnaire,Hair follicle caspase-8, apoptotic (TUNEL+) cell, proliferation (Ki-67+) cell after 1 cycle chemotherapy biopsy and immunohistochemistry | — |
Countries
thailand
Contacts
Public Contactsarun thongvitokomarn
Unaffiliated
Outcome results
None listed