Vertical single-
Conditions
Interventions
The alveolar bone defects are surgically accessed to fully expose the bone augmentation site under oral local anesthesia. The surgical site is prepared for higher bone regeneration potential. A novel
the mucoperiosteal flaps are closured by horizontal mattress suturing and interrupted suturing.
Experimental Procedure/Surgery
surgical procedure of guided bone regeneration
Sponsors
Khon Kaen University, Faculty of Dentistry
Khon Kaen University,
Graduate School,National Metal and Materials Technology Center (MTEC),
Thailand,Khon Kaen University Neural Science Fund
Eligibility
Sex/Gender
All
Age
20 Years to 67 Years
Inclusion criteria
Inclusion criteria: Generally healthy adult patients (ASA â… , â…¡) ranging 20-65 years old; Good oral hygiene and periodontal conditions (full-mouth plaque and bleeding score ≤ 25%); Single-tooth vertical or combined alveolar defect in posterior mandible; Alveolar bone defects ranging 2-6 mm below buccal cemento-enamel junction (CEJ) connection line of two adjacent teeth. Narrow flat edentulous ridge leads to larger crown-implant ratio, unsatisfactory esthetics, unpredictable implant integration and long-term prognosis than normal ridge; Available bone height smaller than implant length selected;
Exclusion criteria
Exclusion criteria: Severe systemic disorders that contraindicate oral surgeries; History of head and neck malignancy and related chemoradiotherapy; Long-term use of steroid or immunological therapy (≥ 6 months); Severe osteoporosis (≥ 2 fragility fractures); Oral / intravenous bisphosphonate therapy ≥ 5 years; Pregnancy and lactation for female patients; Interocclusal restoration height available < 4.0 mm at edentulous area; Severe tempromandibular joint (TMJ) disorders and parafunctions; Bone augmentation procedure at the same site within the past one year; Additional soft tissue augmentation procedures at the same site within the past six months; Active, acute mucosal, periodontal and skeletal lesions; Heavy drinkers (≥ 1 drink / day for women or 2 drinks / day for men); Heavy smokers (≥ 10 cigarettes / day).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| DMB (distance from matrix to bone) 1. During GBR procedure; 2. 6 months after GBR periodontall probe (0.1 mm),Attachd Gingival Width (AGW) 1. During GBR procedure; 2. 6 months after GBR periodontal probe (0.1 mm),Horizontal Alveolar Width (HAW) 1. During GBR procedure; 2. 6 months after GBR periodontal probe (0.1 mm),Available Bone Height (ABH) 1. During GBR procedure; 2. 6 months after GBR CBCT (0.1 mm) | — |
Secondary
| Measure | Time frame |
|---|---|
| Implant stability quotient (ISQ) 1.at implant placement; 2. 4 months after implant placement Resonance Frequency Analysis (Osstell ISQ),Mesial Implant Exposure (MIE): 1.at implant placement; 2. 4 months after implant placement periapical film,Distal Implant Exposure (DIE): 1.at implant placement; 2. 4 months after implant placement periapical film,Buccocclusal area (BOA) 1. baseline before GBR; 2 6 months after GBR intraoral scanning (3Shape),Buccoapical area (BAA) 1. baseline before GBR; 2 6 months after GBR intraoral scanning (3Shape),Lingocclusal area (LOA) 1. baseline before GBR; 2 6 months after GBR intraoral scanning (3Shape),Lingoapical area (LAA) 1. baseline before GBR; 2 6 months after GBR intraoral scanning (3Shape),New bone percent (NB%) 6 months after GBR histomorphometry,Allograft particle percent (AP%) 6 months after GBR histomorphometry,Marrow space percent (MS%) 6 months after GBR histomorphometry,Connective tissue percent (CT%) 6 months after GBR histomorphometry | — |
Countries
Thailand
Contacts
Public ContactJichuan Song
Faculty of Dentistry, Khon Kaen Univesity
Outcome results
None listed