Hepatocellular carcinoma patients who eligible for Tranarterial chemoembolization. HCC TACE prophylaxis steroid
Conditions
Interventions
Dexamethasone 8 mg to prevent PES,Normal saline in the same shape ,
color and amount compare to intevention.
Experimental Drug,Placebo Comparator No treatment
Dexamethasone,Nornal saline
Sponsors
None listed
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Hepatocellular carcinoma patients who eligible for Tranarterial chemoembolization.
Exclusion criteria
Exclusion criteria: 1.patient with Child-Pugh class C 2.patient with active upper gastrointestinal bleeding 3. patient with metastatic HCC 4. patient with encephalopathy 5. patient with refractory ascites 6. patient with intrahepatic duct dilatation 7.patient with TB > 2 mg/dl 8. patient with major portal vein thrombosis 9.patient who is not eligible for TACE
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Effectiveness of dexamethasone in prevention of postembolization syndrome 48 hours after intervention Southwest oncology group toxicity coding score | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of hospitalization between groups at least 1 week after intervention hospitalized duration in day | — |
Countries
Thailand
Contacts
Public ContactPanot Sainamthip
Phramongkutklao College of Medicine
Outcome results
None listed