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The Effect of Psyllium Fiber Supplementation on Diarrhea in the Enteral-Tube Fed Patients: A prospective, Randomized, and Controlled Trial

The Effect of Psyllium Fiber Supplementation on Diarrhea in the Enteral-Tube Fed Patients: A prospective, Randomized, and Controlled Trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20170821004
Enrollment
82
Registered
2017-08-21
Start date
2017-05-01
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hospitalized patients who receive enteral nutrition via tube feeding (nasogastric tube or orogastric tube) Fiber Enteral Nutrition Psyllium Diarrhea Blendera Tube feeding Nosocomial diarrhea

Interventions

Mucilin&#45
mixed blendera,Blendera
Active Comparator Drug,Placebo Comparator No treatment
added formula ,General formula

Sponsors

Faculty of Medicine, Prince of Songkla University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: - Patients at least 18 years of age - Receiving enteral nutrition via tube feeding (nasogastric tube or orogastric tube) - Expected to receive enteral feeding of at least 5 days

Exclusion criteria

Exclusion criteria: &#45; Refuse to participate in the study &#45; Hemodynamic instability at the time of enteral tube feeding initiation (a mean arterial pressure (MAP) value less than 50 mmHg&#44; or escalating doses of vasopressor/inotropic agent(s) requirement to maintain a MAP value more than 50 mmHgwithin 24 hours) &#45; Impossibility to use the gastrointestinal tract (hemorrhage&#44; obstruction&#44; severe ileus) &#45; Recent acute pancreatitis (within 2 weeks) or Chronic pancreatitis &#45; Known diarrheal illness causes by pre&#45;existing gastrointestinal pathology (e.g. ulcerative colitis&#44; Crohn&#39;s disease&#44; ischemic or infectious colitis) &#45; Enteric fistula &#45; Patients with restricted enteral fluid intake < 1&#44;500 ml/day &#45; Pregnancy &#45; Inability to distinguish between stool and urine during defecation

Design outcomes

Primary

MeasureTime frame
proportion of patients with at least 1 day of diarrhea in enterally fed patients 10 days after start enteral feeding or death or discharge or change to oral diet KIng&#39;s stool chart

Secondary

MeasureTime frame
percentage of days with diarrhea per total feeding days in enterally fed patients 10 days after start enteral feeding or death or discharge or change to oral diet KIng&#39;s stool chart

Contacts

Public ContactPimsiri Sripongpun

Prince of Songkla University

pim072@hotmail.com66973450072

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Apr 4, 2026