Degenerative lumbar spine
Conditions
Interventions
Before closure of the surgical wound,
the experimental group received an absorbable gelfoam soaked with a 1 ml (5 mg) of dexamethasone and 0.5% bupivacaine diluted to 2 ml placed on the epidural space.
,Before closure of the surgical woun
the placebo group received an absorbable gelfoam soaked with normal saline 2 ml placed on the epidural space.
Experimental Drug,Placebo Comparator Drug
Sponsors
Department of Orthopaedics Faculty of Medicine Chiang Mai University
Department of Orthopaedics Faculty of Medicine Chiang Mai University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.) Age ≥ 18 2.) ASA physical status I or II 3.) Can operate patient-controlled analgesia (PCA) device 4.) Degenerative condition of spinal disease 5.) No previous spinal surgery
Exclusion criteria
Exclusion criteria: 1.) Allergy to steroid or bupivacaine or morphine 2.) Prohibit to substance made from pig e.g. Muslim 3.) Pregnancy or lactating 4.) Infection, trauma or tumor spinal condition 5.) History previous spinal surgery 6.) Smoking
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparison pain intensity in 48 hrs post-op by use Numeric rating scale 48 hr postoperation Pain scores (Use Numerical Rating Scale) were recorded postoperatively at 8, 16, 24 and 48 hr | — |
Secondary
| Measure | Time frame |
|---|---|
| Comparison Morphine consumption dose(mg) in 48 hrs post-op 48hr post operation Morphine consumption dose(mg) were recorded postoperatively at 8, 16, 24 and 48 hr,Incidence of surgical site infection in 1 month post-op and pseudathrosis at 6 month post-op 1 month post-op for surgical site infection and 6 month post-op for pseudarthrosis follow up patients at out patients clinic and observe for complication | — |
Countries
Thailand
Contacts
Public ContactNattharut Chaibhuddanugul
Department of Orthopaedics faculty of Medicine Chiang Mai university
Outcome results
None listed