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The Association between Pre-treatment Dietary Behavior and Taste Alteration in Thai Head and Neck Cancer Patients Who Underwent Radiotherapy

The Association between Pre-treatment Dietary Behavior and Taste Alteration in Thai Head and Neck Cancer Patients Who Underwent Radiotherapy

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20170801003
Enrollment
Unknown
Registered
2017-08-01
Start date
2017-01-15
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

head and neck cancer radiation therapy taste alteration TASTE PREFERENCE UMAMI THRESHOLD RADIOTHERAPY NUTRITION STATUS HEAD AND NECK CANCER

Interventions

head and neck cancer patients undergoing radiation therapy
Supportive Care
head and neck cancer patients

Sponsors

Research and Education Unit on Sensory Sciences for Better Nutrition, Institute of Nutrition, Mahido
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: - Age over 18 years - Diagnosed with head and neck cancer - No history of cancer treatment during the past 6 months - Have treatment plan for radiotherapy which is expected to have taste alteration as complication - Able to communicate in Thai and sign the consent form - Resided in Thailand during the past 5 years

Exclusion criteria

Exclusion criteria: - Loss of all taste sensation prior to radiotherapy - Unable to tolerate the test - Taking medicines affecting taste as side effects during the past one week prior to radiation, including cyclophosphamide, cisplatin, etoposide, zopiclone, azelastine, emedastine, amiloride, penicillamine, captopril, metronidazole, chlorhexidine, eprosartan

Design outcomes

Primary

MeasureTime frame
changes in recognition thresholds 0-400, 1000-2000, 2800-3400, 4000-4400, and 5000-7000 cGy of radiation and 2 month-follow up after r filter paper disc,changes in body weight 0-400, 1000-2000, 2800-3400, 4000-4400, and 5000-7000 cGy of radiation and 2 month-follow up after r weight scale,preference in spicy, umami, sweet, salty, sour, bitter before radiation therapy validated questionnaire (Taste-26)—

Secondary

MeasureTime frame
changes in PG-SGA score 0-400, 1000-2000, 2800-3400, 4000-4400, and 5000-7000 cGy of radiation and 2 month-follow up after r PG-SGA questionaire and exam,changes in energy intake 0-400, 1000-2000, 2800-3400, 4000-4400, and 5000-7000 cGy of radiation and 2 month-follow up after r 3-day dietary record—

Countries

Thailand

Contacts

Public ContactDunyaporn Trachootham

Institute of Nutrition, Mahidol University, Thailand

dunyaporn.tra@mahidol.ac.th66846953647

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026