advanced solid cancer patients epidermal growth factor receptor inhibitors acneiform eruption paronychia hair abnormalities skin dryness pruritus EGFR inhibitors radiotherapy conventional chemotherapy acneiform eruption paronychia hair abnormalities skin dryness pruritus
Conditions
Interventions
advanced solid cancer patients treated with epidermal growth factor receptor inhibitors
Health Services Research
patients treated with epidermal growth factor receptor inhibitors
Sponsors
Quality Improvement Fund, King Chulalongkorn Memorial Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: - advanced solid cancer patients (stage IV) treated with epidermal growth factor receptor inhibitors - above 18 years old
Exclusion criteria
Exclusion criteria: prior to recruit in the study, patients have existing skin conditions including acneiform eruption, paronychia, hair abnormalities, skin dryness and pruritus.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| incidence of cutaneous complications in advanced solid cancer patients treated with EGFRI 2 weeks,4 weeks, 12 weeks, 24 weeks, 48 weeks Clinical manifestation of skin. | — |
Secondary
| Measure | Time frame |
|---|---|
| changes of biophysical properties of the skin in advanced solid CA patients treated with EGFRI 2 weeks, 4 weeks, 12 weeks, 24 weeks, 48 weeks multi probe system Cutometer MPA580, Visia, Visiometer SV 600 | — |
Countries
Thailand
Contacts
Public ContactPawinee Rerknimitr
Faculty of Medicine, Chulalongkorn University
Outcome results
None listed