Endometriotic cyst Endometriosis Combine oral pills Endometrioma Autophagy
Conditions
Interventions
combined pill composed of ethinyl estradiol 0.03 mg and Drospirenone 3 mg,No treatment for women who has at least one endometrioma,No treatment for women who has at least one benign ovarian tumor
Experimental Drug,No Intervention No treatment,No Intervention No treatment
Yasmin,Endometrioma, not treated,Benign cyst, not treated
Sponsors
Faculty of Medicine, Ramathibodi Hospital
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. No pregnant with intact uterus women age 20-40 years with endometriotic cyst needed laparoscopic surgery 2. Has suspected ovarian endometrioma diagnosed by ultrasonography size at least 3 cm 3. Regular menstrual cycle for more than 3 consecutive months 4. No oral hormonal treatment for at least 3 months, depot-medroxyprogesterone acetate (DMPA) or GnRH agonist for at least 6 before surgery 5. No NSAIDS treatment for at least 3 months before surgery 6. Willing to participate
Exclusion criteria
Exclusion criteria: 1. Women with underlying diseases such as DM, HT, thrombosis, abnormal coagulation, heart disease, liver and gall bladder disease, cerebral arterial/venous diseases, cancer. 2. Contraindication for oral combine pills such as allergy to pill, abnormal vaginal bleeding, endometrial hyperplasia 3. Abnormal pap smear 4. Drink alcohol or smoking 5. Pathology result not endometriosis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| LCIII, Beclin-1, Atg gene and protein expression 1 year RT-PCR, western blot and immunohistochemistry | — |
Secondary
| Measure | Time frame |
|---|---|
| N/A N/A N/A | — |
Countries
Thailand
Contacts
Public ContactAreepan Sophonsritsuk
Faculty of Medicine, Ramathibodi Hospital
Outcome results
None listed