Healthy Adult patients Vibration Receptor Activator of Nuclear Kappa-
Conditions
Interventions
The patients who needed extraction of bilateral maxillary first premolars for canine distalization with fixed orthodontic appliance on 16x22 Stainless steel wire. Each patient was again randomized to
controller at 30 Hertz. ,The patients who needed extraction of bilateral maxillary first premolars for canine distalization with fixed orthodontic appliance on 16x22 Stainless steel wire. Each patient
controller at 60 Hertz.,The patients who needed extraction of bilateral maxillary first premolars for canine distalization only with fixed orthodontic appliance on 16x22 Stainless steel wire.
Orthodontic treatment combines with vibration at 30 Hertz,Orthodontic treatment combines with vibration at 60 Hertz,Orthodontic treatment only
Sponsors
Graduate School, Prince of Songkla University
Faculty of Dentistry,Prince of Songkla University
Eligibility
Sex/Gender
All
Age
18 Years to 30 Years
Inclusion criteria
Inclusion criteria: - The patients who have malocclusion, which need the extraction of right and left upper first premolar for upper canine retraction. - The age of patients are between 18-30 years. - No signs and symptoms of periodontal disease follow by American academy of periodontology (AAP) 1990. - No other bone diseases. - No drug allergy and long term use of anti-inflammatory, immunosuppressive, bisphosphonates and steroid drugs especially 6 months before started treatment.
Exclusion criteria
Exclusion criteria: - Un-cooperative patients. - The participants are unable to continue treatment. - Loss follows up. - Unable to control oral hygiene. - Presence of periodontal diseases during study. - Failure of bonding on the maxillary canine.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| RANKL:OPG ratio Before bracket placement(T0), Before canine retraction(T1), 24 hours(T2), 48 hours(T3), 7 days(T4), Picogram/microlite | — |
Secondary
| Measure | Time frame |
|---|---|
| Rate of canine movement before canine retraction(T1) and 3 months canine retraction(T6) millimeters/month,Rate of molar movement before canine retraction(T1) and 3 months canine retraction(T6) millimeters/month,Canine angulation before canine retraction(T1) and 3 months canine retraction(T6) degree,Molar angulation before canine retraction(T1) and 3 months canine retraction(T6) degree,Canine rotation before canine retraction(T1) and 3 months canine retraction(T6) degree | — |
Countries
THAILAND
Contacts
Public ContactNatchanon Siriphan
Faculty of Dentistry, Prince of Songkla University
Outcome results
None listed