Active kidney disease that need further investigation by kidney biopsy. kidney biopsy cephalic direction caudal direction
Conditions
Interventions
Participant lie prone. The operator use real-
time ultrasound technique for kidney biopsy. The tip of kidney biopsy needle is pointed to legs and 45-
60 degree with participant'
s back. The needle cut tissue at lower pole of kidney.,Participant lie prone. The operator use real-
time ultrasound technique for kidney biopsy. The tip of kidney biopsy needle is pointed to head and 45-
s back. The needle cut tissue at lower pole of kidney.
Experimental Procedure/Surgery,Experimental Procedure/Surgery
Kidney biopsy: Caudal direction technique.,Kidney biopsy: Cephalic direction technique.
Sponsors
Research Facilitation Division, Faculty of Medicine Vajira Hospital.
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Participant is sent for kidney biopsy due to indication: glomerulonephritis nephrotic syndrome rapidly progressive glomerulonephritis unexplained cause of acute kidney injury unexplained cause of proteinuria follow up after treatment
Exclusion criteria
Exclusion criteria: 1. Serum creatinine > 3.5 mg/dL (duration > 3 months) 2. Kidney size by ultrasound is below than 8 centimeters in length, 3.5 centimeters in width or cortex thickness below 0.8 centimeters. 3. Prothrombin time (PT) > 13.5 seconds,activated partial thromboplastin time (aPTT) > 40 seconds or international normalization ratio (INR) ≥ 1.5 4. Platelet ≤ 100,000/uL 5. Current medication: Aspirin, clopidogrel, warfarin, heparin, LMWH, direct thrombin inhibitor 6. concomitant disease: acquired or congenital platelet dysfunction, bleeding disorder. ึ7. Kidney transplant status. 8. systolic blood pressure > 160 mmHg or diastolic blood pressure >110 mmHg 9. Body Mass Index > 35 kg/m2 10.Pregnant 11.Active infection (7 days) 12.skin and soft tissue infection locate at biopsy area. 13.Single kidney participant 14.Hemoglobin < 8 g/dL 15.Structural abnormality of kidney 16.un-cooporate participant 17. deny consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| number of glomeruli immediately pathology reports | — |
Secondary
| Measure | Time frame |
|---|---|
| adequacy of kidney tissue. immediately pathology report,complication (hematuria, perinephric hematoma and obstructive uropathy) 24 hours ultrasound evaluation and clinical evaluation | — |
Countries
Thailand
Contacts
Public ContactWanjak Pongsittisak
Navamindradhiraj University
Outcome results
None listed