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Result of Pre-emptive periarticular multimodal drug injection for postoperative pain management in simultaneous bilateral TKA

Result of Pre-emptive periarticular multimodal drug injection for postoperative pain management in simultaneous bilateral TKA

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20170617001
Enrollment
45
Registered
2017-06-17
Start date
2016-10-31
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients who had knee pain with diagnosis of osteoarthritis and were scheduled for simultaneous bilateral TKA. simultaneous bilateral TKA&#44

Interventions

The patients undergo simultaneous bilateral TKA and have periarticular multimodal drugs injection into one knee after all the cut are finished. ,The patients undergo simultaneous bilateral TKA and ha
Active Comparator Procedure/Surgery,Experimental Procedure/Surgery
Standard PMDI,Pre&#45
emptive PMDI

Sponsors

None
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 85 Years

Inclusion criteria

Inclusion criteria: Patients who had knee pain with diagnosis of osteoarthritis and were scheduled for simultaneous bilateral TKA.

Exclusion criteria

Exclusion criteria: 1.had previous knee surgery 2.had previous infection 3.had allergy to drugs used in this study 4.history of deep vein thrombosis 5.history of heart disease 6.history of cerebrovascular disease 7.history of renal disease 8.history of liver disease

Design outcomes

Primary

MeasureTime frame
Pain score 6, 12,24, 48, 72, 96 hour postoperative Visual analoque scale,degree of knee flexion, straight leg raising, extension lag 6, 12,24, 48, 72, 96 hour postoperative Goniometer,Morphine consumption 24, 48, 72, 96 hour postoperative amount of morphine use from PCA

Secondary

MeasureTime frame
morphine consumption 24, 48 hour postoperative amount of morphine released by PCA

Countries

Thailand

Contacts

Public ContactArtit Laoruengthana

Department of Orthopaedics, Faculty of Medicine, Naresuan university

artitlao@gmail.com085-1102799

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026