Intraoperative dexmedetomidine infusion for better recovery in C-spine surgery

Recovery profiles after general anesthesia in patient undergoing c-spine surgery : with or without dexmedetomidine as an anesthetic adjuvant

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

TCTR

Registry ID

TCTR20170607001

Enrollment

100

Registered

2017-06-07

Start date

2016-05-03

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Elective c&#45

Interventions

Dexmedetomidine 0.5 mcg/kg loading in 30 min Then 0.5 mcg/kg/h until 30 min before operation finish,NSS loading and continous drip at same rate and volume as group 1

Experimental Drug,Placebo Comparator Drug

Dexmeditomidine group,NSS group

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Elective c-spine surgery, Age 18-70 years old, ASA I-III, Not recieve any pain control, sedative or hypnotic medications 24 hours prior to surgery , Expect to be extubated after surgery

Exclusion criteria

Exclusion criteria: Previous c-spine surgery,Poor controlled hypertension (SBP > 140 mmHg at ward),HR 30 kg/m2

Design outcomes

Primary

Measure	Time frame
Quality of emergence before and after extubation Riker sedation agitation scale	—

Secondary

Measure	Time frame
Anesthetic, pain control drugs requirement 24 hours postoperative milligrams	—

Countries

Thailand

Contacts

Public ContactBusara Sirivanasandha

Department of Anesthesiology, Faculty of Medicine Siriraj Hospital, Mahidol University

busarasiri@yahoo.com0851429656

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026

Intraoperative dexmedetomidine infusion for better recovery in C&#45;spine surgery