Effect of Milk and Yogurt Contained Probiotics Lactobacillus rhamnosus SD11 on Mutans Streptococci in children 12-14 years old

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

TCTR

Registry ID

TCTR20170601002

Enrollment

200

Registered

2017-06-01

Start date

2017-06-12

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Level of mutans streptococci caries status side effect persistant probiotics mutans streptococci caries status children

Interventions

subjects were randomly assigned to group A or B or C or D&#44

Group A drank 5 g reconstituted milk powder with probiotic L. rhamnosus SD11 once daily for 3 month,subjects were randomly assigned to group A or B or C or D&#44

Group B drank 5 g reconstituted milk powder once daily for 3 month,subjects were randomly assigned to group A or B or C or D&#44

Group C drank 100 ml reconstituted yogurt with probiotic L. rhamnosus SD11 once daily for 3 month,subjects were randomly assigned to group A or B or C or D&#44

Group D drank 100 ml reconstituted yogurt once daily for 3 month

Experimental Dietary Supplement,Placebo Comparator Dietary Supplement,Experimental Dietary Supplement,Placebo Comparator Dietary Supplement

milk powder contained probiotic Lactobacillus rhamnosus SD11,milk powder,yogurt contained probiotic Lactobacillus rhamnosus SD11,yogurt

Eligibility

Sex/Gender

All

Age

12 Years to 14 Years

Inclusion criteria

Inclusion criteria: Subjects are 12-14 years old good general health condition subjects have dental caries â‰¤ 2 teeth

Exclusion criteria

Exclusion criteria: The exclusion criteria were i systemic diseases related with immunity problem or severe chronic diseases ii allergy to cows milk, lactose intolerance, severe food allergy iii systemic antibiotic medication taken within 2 weeks iv habitual consumption of probiotics and xylitol

Design outcomes

Primary

Measure	Time frame
decrease oral pathogen (persistant and side effect) at the end and 3, 9 months after end of the intervention cariogenicpathogen evaluation, immunity in saliva	—

Secondary

Measure	Time frame
prevention of dental caries at 3, 9 months after end of the intervention assessment of dental status	—

Countries

Thailand

Contacts

Public ContactRawee Teanpaisan

Faculty of Dentistry, Princeof Songkla University

rawee.t@psu.ac.th66+74+287581

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026

Effect of Milk and Yogurt Contained Probiotics Lactobacillus rhamnosus SD11 on Mutans Streptococci in children 12&#45;14 years old