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Association of ABO blood group system and ABO polymorphisms with angiotensin converting enzyme activity in Thai population

Association of ABO blood group system and ABO polymorphisms with angiotensin converting enzyme activity in Thai population

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20170523001
Enrollment
Unknown
Registered
2017-05-23
Start date
2017-05-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ACE inhibitor&#45

Interventions

Healthy volunteers (aged between 19&#45
45 years) will be recruited in the study. All the study participants are Thai. People with hypertension&#44
heart disease&#44
pregnancy&#44
lactation&#44
smoking&#44
drinking alcohol will be excluded. Becasue of these affects angiotensin converting enzyme activity.
Basic Science
Thai healthy volunteers

Sponsors

National Science and Technology Development Agency (NSTDA)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
19 Years to 45 Years

Inclusion criteria

Inclusion criteria: Thai healthy volunteers

Exclusion criteria

Exclusion criteria: 1. Drinking alcohol, smoking, drug abuse 2. Pregnancy, lactation, hormonal contraceptive use 3. Steroid and herbal medicines esp. Centella asiatica use within 2 weeks before blood collection 4. Underlying diseases: hypertension, cardiovascular disease, thyroid disease, diabetes mellitus, pulmonary disease, cirrhosis, leprosy, AIDS, cancer

Design outcomes

Primary

MeasureTime frame
Angiotensin converting enzyme activity end of experiment Spectrophotometer assays—

Secondary

MeasureTime frame
ABO polymorphisms end of experiment Real-time PCR based allelic discrimination—

Countries

Thailand

Contacts

Public ContactAmmara Chaikan

Thammasat University, Thailand

ammarachaikan@hotmail.com662-926-9710-1

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026