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Prevalence of somatic KCNJ5 mutations in patients with aldosterone-producing adenoma in King Chulalongkorn Memorial Hospital

Prevalence of somatic KCNJ5 mutations in patients with aldosterone-producing adenoma in King Chulalongkorn Memorial Hospital

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20170522002
Enrollment
Unknown
Registered
2017-05-22
Start date
2016-10-13
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Prevalence of somatic KCNJ5 mutations Resolution of hypertension and hypokalemia at one year after surgery Clinical characteristics of patients with and without somatic KCNJ5 mutations aldosterone&#45

Interventions

&#45
Adults aged 18 years old or older &#45
Diagnosed APA according to an Endocrine Society practice guidelines1 &#45
Underwent unilateral adrenalectomy in KCMH from 2006&#45
2016 &#45
Had adrenal tissues for DNA sequencing
Diagnostic
Patients with aldosterone&#45
producing adrenal adenoma that underwent unilateral adrenal adenoma

Sponsors

Ratchadapiseksompotch Fund
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Adults aged 18 years old or older Diagnosed APA according to an Endocrine Society practice guidelines1 Underwent unilateral adrenalectomy in KCMH from 2006-2016 Had adrenal tissues for DNA sequencing

Exclusion criteria

Exclusion criteria: patients with postoperative persistent hyporeninemic hyperaldosteronism

Design outcomes

Primary

MeasureTime frame
prevalence of somatic KCNJ5 mutations in patients with aldosterone-producing adenoma one year genetic study—

Secondary

MeasureTime frame
clinical characteristics of patients with somatic KCNJ5 mutations one year chart review and case record form—

Countries

Thailand

Contacts

Public ContactWasita Warachit

None

doctorwasita@gmail.com668100948585

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026