The Efficacy of Tibial nerve block and Obturator nerve block combined with Continuous adductor canal block after Total knee arthroplasty : A Randomized controlled trial.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

TCTR

Registry ID

TCTR20170515002

Enrollment

Registered

2017-05-15

Start date

2017-05-26

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

total knee arthroplasty continuous adductor canal block obturator nerve block tibial nerve block total knee arthroplasty postoperative pain control postoperative rehabilitation postoperarive functional outcome continuous adductor canal block obturator nerve block tibial nerve block

Interventions

Continuous adductor canal block :We placed ultrasound probe at middle point between Superior anterior iliac spine and base of patella and identified Sartorius muscle&#44

Saphenous nerve&#44

Femoral artery and vein. After that we painted field with antiseptic and used 80 mm Touhy needle with PERIFIX 20&#45

24 Ga. Epidural catheter (B.Braun Medical&#44

Inc.&#44

Bethlehem&#44

PA)&#44

in&#45

plane technique to proper position&#44

inferior to Sartorius muscle and superior to Femoral artery&#44

then injected NSS for checked position of needle. The next step&#44

we inserted epidural catheter and inject 0.25% levobupivacaine 15 ml with intermittent negative aspiration. Last step&#44

the catheter was fixed with skin and 0.15% levobupivacaine was injected continuously 5 ml/hr with disposable infusion pump (COOPDECH syrinjector). Single shot Obturator nerve block under high frequenc

inch (100mm) insulated Stimuplex needle &#44

0.25% levobupivacaine 15 ml was injected at recovery room.,Continuous adductor canal block :We placed ultrasound probe at middle point between Superior anterior iliac spine and base of patella and ide

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: patient who was scheduled for total knee arthroplasty at King Chulalongkorn Memorial Hospital American Society of anesthesiologist ASA class 1 to 3 o ASA class 1 A normal healthy patient non smoking no or minimal alcohol use o ASA class 2 A patient with mild systemic disease Mild diseases only without substantive functional limitations Examples include but not limited to current smoker social alcohol drinker pregnancy obesity 30 BMI 40 well controlled DM HTN mild lung disease o ASA class 3 A patient with severe systemic disease but not threaten to life poorly controlled DM or HTN COPD morbid obesity BMI 40 active hepatitis alcohol dependence or abuse implanted pacemaker moderate reduction of ejection fraction ESRD undergoing regularly scheduled dialysis premature infant PCA 60 weeks history 3 months of MI CVA TIA or CAD stents o Body mass index (BMI) between 18 to 40 kg/m2

Exclusion criteria

Exclusion criteria: o refuse to participate this study o allergy to any drug in this study o contraindication to neuraxial anesthesia eg.coagulopathy o contraindication to NSAIDs (Dynastat and Celebrex in this study) for example history of heart failure, cerebrovascular disease, heart or coronary artery surgery, history of peptic ulcer, abnormality of liver enzyme, liver or renal failure, organ transplantation and coagulopathy. o chronic opioids use (definition : daily or almost opioids use for more than three months or morphine use more than 60 miligrams per day for more than 1 months) or diagnosed of neuropathic pain o unable to performed Time up and go test

Design outcomes

Primary

Measure	Time frame
Postoperative morphine consumption 24 hours Postoperative 24 hours miligram of morphine consumption using PCA device	—

Secondary

Measure	Time frame
Postoperative morphine consumption 48 hours Postoperative 48 hours miligram of morphine consumption using PCA device,Pain score postoperative 6,12,18 hour postoperative 0, 30 minutes 1,4,8,12,16 hours visual analog scale,Pain score at rest, stand, walk of the knee postoperative 18 h postoperative visual analog scale,Pain score at rest, stand, walk postoperative postoperative day 1,2 visual analog scale,Quadriceps strength postoperative day 1, 2, 3 postoperative 18 h, day 1, 2 maximum voluntary isometric contraction,Degree of knee flexion (active and passive) postoperative day1,2,3 postoperative 18 h, day 1, 2 degree of range of motion,Rehabilitation after surgery postoperative 18 h, day 1, 2 The Timed Up and Go test (TUG),Rehabilitation after surgery postoperative 18 h, day 1, 2 The Timed Up and Go test (TUG)	—

Measure

Time frame

Postoperative morphine consumption 48 hours Postoperative 48 hours miligram of morphine consumption using PCA device,Pain score postoperative 6,12,18 hour postoperative 0, 30 minutes 1,4,8,12,16 hours visual analog scale,Pain score at rest, stand, walk of the knee postoperative 18 h postoperative visual analog scale,Pain score at rest, stand, walk postoperative postoperative day 1,2 visual analog scale,Quadriceps strength postoperative day 1, 2, 3 postoperative 18 h, day 1, 2 maximum voluntary isometric contraction,Degree of knee flexion (active and passive) postoperative day1,2,3 postoperative 18 h, day 1, 2 degree of range of motion,Rehabilitation after surgery postoperative 18 h, day 1, 2 The Timed Up and Go test (TUG),Rehabilitation after surgery postoperative 18 h, day 1, 2 The Timed Up and Go test (TUG)

—

Countries

Thailand

Contacts

Public Contactwireena Kampitak

Faculty of medicine, Chulalongkorn University

nutong127@yahoo.com6689-9955-666

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Apr 4, 2026