Effect of sildenafil on the healing of digital ulcer in Thai systemic sclerosis

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20170426001

Enrollment

Registered

2017-04-26

Start date

2017-04-26

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Efficacy Digital ulcer Sildenafil Systemic sclerosis Scleroderma Quality of life

Interventions

Sildenafil GPO 20 mg

Experimental Drug

Sidenafil GPO

Eligibility

Sex/Gender

All

Age

18 Years to 100 Years

Inclusion criteria

Inclusion criteria: An active digital ulcer in SSc patients age over 18 years old On-going nifedipine treatment, but no response

Exclusion criteria

Exclusion criteria: Smoking within 3 months before the study Hypotension Arrhythmia Traumatic ulcer Infection

Design outcomes

Primary

Measure	Time frame
healing of digital ulcers every 4 weeks counting number of digital ulcers	—

Secondary

Measure	Time frame
new digital ulcers every 4 weeks couting number of digital ulcers	—

Countries

Thailand

Contacts

Public ContactSittichai Netwijitpan

Faculty of Medicine,Khon Kaen University

sittne@kku.ac.th0895708899

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026