Patients with ovarian endometriotic cyst Combined oral contraceptive pill Endometriotic cysts Combined oral contraceptive pill
Conditions
Interventions
No treatment will be given to the control group.,1 tab per day of combined pill composed of ethinyl estradiol 0.03 mg and Desogestrel 0.15 mg for 28-
32 days before surgery
Treatment,Treatment
Control,Combined pill
Sponsors
Department of Obstetrics and Gynecology, Faculty of Medicine, Ramathibodi Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Healthy female subjects age 18-45 years old. 2. Subjects who were diagnosed with endometriotic cyst with size equal or more than 3 centimeters. 3. Subjects who have no previous records of taking any kinds of hormones during 3 months prior to the study and those who were not recieved depot-medroxyprogesterone acetate (DMPA) or GnRHa within 9 months prior to the study. 4. Subjects who have no limitations in taking either ethinyl estradiol with Desogestrel. 5. Subjects who are willing to participate in the study program.
Exclusion criteria
Exclusion criteria: 1. Subjects with underlying disease that contraindicate to receive ethinyl estradiol and desogestrel such as Cirrhosis, Chronic kidney disease, Coagulopathy, Heart disease and Pulmonary disease. 2. Subjects who have contraindication to taking either ethinyl estradiol and desogestrel 3. Subjects who are intolerable to irregularity of menstruation cycle. 4. Subjects who rejected or withdrew from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of macrophages 1 month Immunohistochemistry | — |
Secondary
| Measure | Time frame |
|---|---|
| Number of FoxP3 cells 1 month Immunohistochemistry,Number of NK cells 1 month Immunohistochemistry | — |
Countries
Thailand
Contacts
Public ContactAreepan Sophonsritsuk
Faculty of Medicine, Ramathibodi Hospital
Outcome results
None listed