The glycemic effect of post-meal walking with basal insulin compared to basal plus regimen in type 2 diabetes: a Randomized controlled cross-over study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

TCTR

Registry ID

TCTR20170419003

Enrollment

Registered

2017-04-19

Start date

2017-04-25

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

glycemic controlled post&#45

Interventions

&#45

The subjects must walk after the heaviest meal of the day for 15&#45

20 minutes at least 1 meal / day&#44

everyday for 6 weeks &#45

The subjects have to continue their basal insulin in the same dose,&#45

The subjects have to use bolus insulin (rapid acting insulin) before the heaviest meal of the day every day &#45

The subjects have to continue their basal insulin in the same dose

Experimental Behavioral,Active Comparator Drug

post&#45

meal walking with basal insulin,basal plus regimen

Eligibility

Sex/Gender

All

Age

35 Years to 70 Years

Inclusion criteria

Inclusion criteria: - type 2 diabetes with at least 2 oral hypoglycemic drugs - FPG < 150 mg/dL for 2 consecutive blood test before enrollment - No adjustment of basal insulin or oral hypoglycemic drugs for 3 months - HbA1c 7-9% - BMI 18.5-30 kg /m2 - Eligible participant

Exclusion criteria

Exclusion criteria: - Severe uncontrolled hypertension (SBP > 160 mmHg or DBP > 100 mmHg) - Acute myocardial infarction or cerebrovascular disease in 6 months - Functional status class II - musculoskeletal problem that affected walking - Visual problem that affected walking - Decrease pinprick sensation or other diabetic neuropathy - History of severe diabetic foot ulcer / history of amputation - treatment with systemic corticosteroid - history of drug abuse - drinking alcohol more than 7 drinks per week - night shift - on premixed or basal bolus insulin - on GLP-1 agonist - on alpha-glucosidase inhibitor - the subjects denied to participate in trial

Design outcomes

Primary

Measure	Time frame
HbA1c at 0 and 6 weeks blood test, Turbidimetric inhibition immunoassay	—

Secondary

Measure	Time frame
serum fructosamine 0,3,6 week blood test, chemiluminescence,2-hour mean PPPG every meal / day, once a week, total 6 weeks capillary blood glucose,24-hour mean plasma glucose premeal and 2 hour postpandrial every meal, once a week, total 6 weeks capillary blood glucose,postpandrial plasma glucose 1,2,3, and 4 hours after standardized meal at 0 and 6 weeks blood test, Hexokinase/Glucose-6-Phosphate Dehydrogenase (HK/G6P-DH) ,Triglyceride 1,2,3, and 4 hours after standardized meal at 0 and 6 weeks blood test, accelerator selective dependent method ,Hypoglycemia event N/A History of symptom and capillary blood glucose during symptom,Weight, waist circumference and BMI 0 and 6 weeks measure by investigator	—

Measure

Time frame

serum fructosamine 0,3,6 week blood test, chemiluminescence,2-hour mean PPPG every meal / day, once a week, total 6 weeks capillary blood glucose,24-hour mean plasma glucose premeal and 2 hour postpandrial every meal, once a week, total 6 weeks capillary blood glucose,postpandrial plasma glucose 1,2,3, and 4 hours after standardized meal at 0 and 6 weeks blood test, Hexokinase/Glucose-6-Phosphate Dehydrogenase (HK/G6P-DH) ,Triglyceride 1,2,3, and 4 hours after standardized meal at 0 and 6 weeks blood test, accelerator selective dependent method ,Hypoglycemia event N/A History of symptom and capillary blood glucose during symptom,Weight, waist circumference and BMI 0 and 6 weeks measure by investigator

—

Countries

Thailand

Contacts

Public ContactOnnicha Suntornlohanakul

Ramathibodi hospital

onnicha.sun@gmail.com+66877164646

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026

The glycemic effect of post&#45;meal walking with basal insulin compared to basal plus regimen in type 2 diabetes: a Randomized controlled cross&#45;over study