Gastrointestinal disorders,
Conditions
Interventions
0.075% Capsaicin Lotion is used for application at skin area involved with symptomatic neuropathic pain (both feet or/and hands),
everyday for 8 weeks then stop,Placebo Lotion is used for application at skin area involved with symptomatic neuropathic pain (both feet or/and hands),
everyday for 8 weeks then stop
Active Comparator Drug,Placebo Comparator Drug
0.075% Capsaicin Lotion,Placebo
Sponsors
BANGKOK DRUG CO.,LTD
Thammasat University
Eligibility
Sex/Gender
All
Age
20 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. DM type 2 over 1 year 2. Clinical presentation of peripheral sensory such as burning pain 3.DN4 score from 4 points 4.Good consciousness to tell their score with informed consent agreement 5.No adding dosage of previous pain control medications at least 4 weeks 6.HbA1C 6.5-9.0%
Exclusion criteria
Exclusion criteria: 1.Improper application site of skin for topical drugs such as abrasion wound. 2.Allergic history of Capsaicin 3.No intention to join the study with any reasons 4.Other previous medications used that effect to peripheral neuropathy such as Carboplatin, Cisplatin, Colchicine, Dapsone, Etoposide, Ethambutol, Indomethacin, Isoniazid, Lithium, Metronidazole, Phenytoin, Pyridoxine, Statins, Stavudine (d4T) or conditions worsening peripheral nerves following that poor nutritiion, kidney failure, chronic alcholism, vitamin deficiency, Hypothyroidism
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual analog scale (0-100 mm.) at 20 weeks after end of the intervention scale | — |
Secondary
| Measure | Time frame |
|---|---|
| Short-form McGill Pain Questionnaire(SF-MPQ) at 20 weeks after end of the intervention scale,Neuropathic Pain Scale (NPS) at 20 weeks after end of the intervention scale | — |
Countries
Thailand
Contacts
Public ContactAssawin Chomjit
Unaffiliated
Outcome results
None listed