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Incidence of Subclinical and Clinical Acute Kidney Injury by a Novel Kidney Injury Biomarker, urine Neutrophil Gelatinase associated Lipocalin in Multidrug Resistant Septic Patients Treated with Colistimethate Sodium

Incidence of Subclinical and Clinical Acute Kidney Injury by a Novel Kidney Injury Biomarker, urine Neutrophil Gelatinase associated Lipocalin in Multidrug Resistant Septic Patients Treated with Colistimethate Sodium

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20170330003
Enrollment
42
Registered
2017-03-30
Start date
2015-02-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute kidney injury Acute kidney injury Early detection Urine neutrophil gelatinase associated lipocalin Colistimethate Sodium Cut off level

Interventions

Septic patients that use colisthemethate sodium (CMS)
Diagnostic
CMS group

Sponsors

Ratchadaphiseksomphot Endowment Fund
Lead Sponsor
Division of Nephrology&#44
Collaborator
Department of Medicine&#44
Collaborator
Faculty of Medicine&#44
Collaborator
Chulalongkorn University
Collaborator

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: All patients over 18 years of age undergoing CMS treatment for more than 72 hours, eGFR ≥ 30 ml/min/1.73 m2 and hemodynamic stability

Exclusion criteria

Exclusion criteria: CKD stage G4 and G5, ESRD on renal replacement therapy, AKI that required hemodialysis within 24 hours after CMS was prescribed and pregnant patients

Design outcomes

Primary

MeasureTime frame
Incidence of clinical AKI in septic patients after CMS use 26 months serum creatinine—

Secondary

MeasureTime frame
Incidence of subclinical AKI in septic patients after CMS use 26 months uNGAL—

Contacts

Public ContactKhajohn Tiranathanagul

Department of Medicine, Faculty of Medicine, Chulalongkorn University

khajohn_t@hotmail.com022564251

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026