Knee Oa patients vitamin D2 supplementation
Conditions
Interventions
Primary knee OA patients with lower levels of serum 25(OH)D (<30 ng/ml) received 40,
000 IU vitamin D2 (ergocalciferol) per week for 6 months.
Experimental Dietary Supplement
vitamin D2 (ergocalciferol) supplementation
Sponsors
The 90th Anniversary Chulalongkorn University Fund
Faculty of Medicine,
Chulalongkorn University
Eligibility
Sex/Gender
All
Age
50 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Knee OA patients who meet the criteria of American College of Rheumatology 2.Knee OA patients have vitamin D insufficiency (25(OH)D < 30 ng/ml) 3.Individuals capable of giving informed consent on their own behalf 4.Individuals willing to attend in this study
Exclusion criteria
Exclusion criteria: 1.Knee OA patients who have history of knee surgery 2.Known primary hyperparathyroidism 3.Current supplement of vitamin D 4.Kidney disease 5.Liver disease 6.Rheumatoid or other inflammatory arthritis (i.e. septic arthritis, gout). 7.Neurological condition (i.e. Parkinson’s disease, previous stroke) 8.Severe cardiovascular condition (i.e. unstable angina) 9.Amputation of lower limbs 10.Unable to perform physical performance 11.Severe visual or hearing impairment uncorrected
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 25(OH)D levels baseline and 6 months after vitamin D2 supplementation blood sample collection | — |
Secondary
| Measure | Time frame |
|---|---|
| muscle strength and physical performance baseline, 3 and 6 months after vitamin D2 supplementation muscle strength and physical performance tests | — |
Countries
Thailand
Contacts
Public ContactSittisak Honsawek
Faculty of Medicine, Chulalongkorn University
Outcome results
None listed