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Effect of Gentian violet on the treatment of vaginal candidiasis with oral fluconazole: a randomized controlled trial

Effect of Gentian violet on the treatment of vaginal candidiasis with oral fluconazole: a randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
TCTR
Registry ID
TCTR20170324004
Enrollment
200
Registered
2017-03-24
Start date
2017-06-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

vaginal candidiasis vaginal&#44

Interventions

the participant get treatment of vaginal candidiasis with standard regimen&#44
Fluconazole 200 mg oral single dose,the participant get treatment for vaginal candidiasis with standard regimen(Fluconazole200mg oral single dose) combine with apply 1% gentian violet 1ml vaginal
Fluconanzole oral (control),gentian violet (intervention)

Sponsors

Faculty of Medicine Siriraj Hospital
Lead Sponsor
Faculty of Medicine Siriraj Hospital
Collaborator

Eligibility

Sex/Gender
Female
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: female who diagnosed of vaginal candidiasis by wet preparation and include immunocompromised host

Exclusion criteria

Exclusion criteria: - pregnant - female who has history of fluconazole allergy - female with liver disease - female who has history of recurrent vulvo/vaginal candidiasis (at least 4 times per year) - female who has vulval candidiasis

Design outcomes

Primary

MeasureTime frame
success rate of treatment in each population 2 weeks culture for fungus turn to negative

Secondary

MeasureTime frame
recurrent rate of vaginal candidiasis in both population 8 weeks interview the suspected symptoms of vaginal candidiasis by telephone,side effect of gentian violet 2 weeks likert scale

Countries

Thailand

Contacts

Public ContactChenchit Chayachinda

Department of Obstetrics and Gynecology, Faculty of Medicine Siriraj

chenchit.cha@outlook.co.th0863123623

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026